I am the director of urology research at Boston Children's Hospital and a cell biologist and biochemist by training. Research in my laboratory focuses on...
Professor of Biological Chemistry and Molecular Pharmacology
The Adelman lab aims to elucidate how cells react in a rapid yet balanced manner to external signals, at the transcriptional and epigenetic level. We use...
Certain genetic disorders cause widespread disease in the body, but the principle reason for illness and death in early childhood is failure of the blood...
The Aguayo-Mazzucato Lab is interested in studying the aging process of pancreatic beta cells and how it contributes to the development of diabetes.... Read more about Cristina Aguayo-Mazzucato
Our laboratory at Dana-Farber Cancer Institute is a basic and translational oncology laboratory focused on studying pancreatic cancer and other RAS-driven...
The broad focus of the Alt lab is the elucidation of mechanisms that generate antigen receptor diversity in the Immune system and mechanisms that maintain... Read more about Frederick W. Alt
Messenger RNA is in constant flux between different locations and states -- the nucleus and cytoplasm, activation and silencing, translation and decay.... Read more about Paul Joseph Anderson
There is now overwhelming evidence indicating that VEGF, TGFβ, PDGF, and Notch among others, the molecules that are essential for vascular formation, are...
Assistant Professor of Biological Chemistry and Molecular Pharmacology
Protein-Protein Interactions (PPIs) is the Holy Grail of therapeutic intervention, offering a plethora of distinct structural landscapes that can be targeted... Read more about Haribabu Arthanari
Cancer cells display remarkable plasticity allowing them to adapt to ever changing environments. A key feature of this plasticity is their ability to...
Professor of Biological Chemistry and Molecular Pharmacology
The bithorax complex in the fruit fly is a cluster of “homeotic” genes which confer distinct identities on the different segments of the fly. The genes...
Richard and Susan Smith Distinguished Professor of Medicine
In erythrocytes, Protein 4.1R is essential for membrane integrity. Deficiencies cause congenital hemolytic anemia. We have shown that there are many isoforms... Read more about Edward Benz
Bacterial cells come in a wide variety of shapes and sizes. Within a given class, however, cells typically grow and divide in such a way as to maintain...
Though much of what defines a human is encoded in the sequence of our DNA, many additional factors influence how this genetic information is manifest. For... Read more about Bradley E. Bernstein
My laboratory is focused on endothelial cells and how they become disrupted in disease. We also study a normal, yet highly proliferative endothelial cell...
Gustavus Adolphus Pfeiffer Professor of Biological Chemistry and Molecular Pharmacology
The long-term goal of our research program is to understand the molecular logic of signal transduction, focusing on proteins implicated in human disease. The... Read more about Stephen Charles Blacklow
My lab studies how organisms defend against environmental and metabolic stresses, and how these stress defenses influence aging. Most of our work involves...
As a physician-scientist caring for children with chronic disease I am acutely aware of the burden caused by these conditions and the need for improved... Read more about David T. Breault
