We seek to elucidate mechanisms of disease and develop novel therapeutics through understanding underlying processes of innate and adaptive immunity...
Assistant Professor of Stem Cell and Regenerative Biology
Cells in complex mammalian tissues, such as the brain, are spatially organized and dynamic, yet almost all genomic tools lack temporal and spatial resolution.... Read more about Fei Chen
Professor of Biological Chemistry and Molecular Pharmacology
Our laboratory takes molecular approaches to herpesvirus replication and latency. These studies provide excellent models for biological processes in...
Associate Professor in the Department of Molecular Metabolism
Our lab investigates the metabolic mechanisms that regulate cellular and organismal adaptation to physiologic and pathologic stress conditions. Within...
George P. Canellos, MD, and Jean S. Canellos Professor of Medicine
The Ebert laboratory focuses on the molecular basis and treatment of hematologic malignancies, with a particular focus on myelodysplastic syndromes (MDS...
Gregor Mendel Professor of Genetics and of Medicine
A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA...
Assistant Professor of Stem Cell and Regenerative Biology
RNA is an ancient and universal biopolymer that is involved in nearly every aspect of biology. Next to nucleic acids, proteins, and lipids, glycans are...
Our lab focuses on the molecular nature of innate immune interactions between microbial pathogens and the host. Pathogenic bacteria have evolved complex...
Our laboratory focuses on understanding the role that mitochondria play in mammalian aging and disease. Mitochondria are dynamic organelles that provide...
The increasing emergence of bacterial strains resistant to antibiotics is far outpacing our ability to develop novel therapies to treat these infections....
Associate Professor, Department of Pediatric Oncology
Our laboratory research program is centered in understanding the structure and function of ATP-dependent chromatin remodeling complexes, with emphasis on...
Professor of Biological Chemistry and Molecular Pharmacology
For many years our research group has been interested in the molecular mechanisms of various antibiotics and the fundamental cellular processes they inhibit.... Read more about Daniel Kahne
The Mekalanos laboratory is engaged in the analysis of bacterial virulence and functional genomics. The goal of these studies is to understand how pathogenic... Read more about John Mekalanos
Professor of Biological Chemistry and Molecular Pharmacology
Research in the Roberts laboratory is centered on kinases, kinase inhibitors, and cancer. We work in a variety of model systems and utilize approaches varying... Read more about Thomas McCoy Roberts
Elliott T. and Onie H. Adams Professor of Biochemistry and Systems Biology
We seek to use the vast knowledge of biology to predictably design biological systems to enhance our fundamental understanding and to provide solutions...