Assistant Professor of Stem Cell and Regenerative Biology
Cells in complex mammalian tissues, such as the brain, are spatially organized and dynamic, yet almost all genomic tools lack temporal and spatial resolution.... Read more about Fei Chen
Professor of Biological Chemistry and Molecular Pharmacology
Our laboratory takes molecular approaches to herpesvirus replication and latency. These studies provide excellent models for biological processes in...
Our research involves the chemical biology of protein post-translational modifications (PTMs) in the context of signaling, epigenetics, and cancer. We develop... Read more about Philip Cole
Associate Professor in the Department of Molecular Metabolism
Our lab investigates the metabolic mechanisms that regulate cellular and organismal adaptation to physiologic and pathologic stress conditions. Within...
George P. Canellos, MD, and Jean S. Canellos Professor of Medicine
The Ebert laboratory focuses on the molecular basis and treatment of hematologic malignancies, with a particular focus on myelodysplastic syndromes (MDS...
Gregor Mendel Professor of Genetics and of Medicine
A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA...
Our laboratory focuses on understanding the role that mitochondria play in mammalian aging and disease. Mitochondria are dynamic organelles that provide...
The increasing emergence of bacterial strains resistant to antibiotics is far outpacing our ability to develop novel therapies to treat these infections....
Associate Professor, Department of Pediatric Oncology
Our laboratory research program is centered in understanding the structure and function of ATP-dependent chromatin remodeling complexes, with emphasis on...
The Mekalanos laboratory is engaged in the analysis of bacterial virulence and functional genomics. The goal of these studies is to understand how pathogenic... Read more about John Mekalanos
Xander University Professor of Stem Cell and Regenerative Biology
Research in our laboratory focuses on the developmental biology of the pancreas. We wish to understand how the pancreas normally develops and use that...
Mitochondria are tiny organelles found in nearly all cells, serving as the center stage for ATP production, ion homeostasis, and apoptosis. Their composition,... Read more about Vamsi K. Mootha
Professor of Biological Chemistry and Molecular Pharmacology
Research in the Roberts laboratory is centered on kinases, kinase inhibitors, and cancer. We work in a variety of model systems and utilize approaches varying... Read more about Thomas McCoy Roberts
My laboratory uses a stem cell based approach to understand neurodegenerative diseases, particularly orphan diseases such as Spinal Muscular Atrophy, so that... Read more about Lee L. Rubin