We seek to elucidate mechanisms of disease and develop novel therapeutics through understanding underlying processes of innate and adaptive immunity...
Assistant Professor of Stem Cell and Regenerative Biology
Cells in complex mammalian tissues, such as the brain, are spatially organized and dynamic, yet almost all genomic tools lack temporal and spatial resolution.... Read more about Fei Chen
George P. Canellos, MD, and Jean S. Canellos Professor of Medicine
The Ebert laboratory focuses on the molecular basis and treatment of hematologic malignancies, with a particular focus on myelodysplastic syndromes (MDS...
Gregor Mendel Professor of Genetics and of Medicine
A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA...
Our laboratory focuses on understanding the role that mitochondria play in mammalian aging and disease. Mitochondria are dynamic organelles that provide...
The increasing emergence of bacterial strains resistant to antibiotics is far outpacing our ability to develop novel therapies to treat these infections....
The Mekalanos laboratory is engaged in the analysis of bacterial virulence and functional genomics. The goal of these studies is to understand how pathogenic... Read more about John Mekalanos
Xander University Professor of Stem Cell and Regenerative Biology
Research in our laboratory focuses on the developmental biology of the pancreas. We wish to understand how the pancreas normally develops and use that...
Mitochondria are tiny organelles found in nearly all cells, serving as the center stage for ATP production, ion homeostasis, and apoptosis. Their composition,... Read more about Vamsi K. Mootha
Elliott T. and Onie H. Adams Professor of Biochemistry and Systems Biology
We seek to use the vast knowledge of biology to predictably design biological systems to enhance our fundamental understanding and to provide solutions...
We are exploring pathogen-host interactions, particularly in the context of animal models relevant to human infection of clinically important enteric...
Richard Pearson Strong Professor of Infectious Disease
Malaria remains a major public health threat with more than 225 million people infected worldwide and one fourth of the world's population is at risk for...