The broad focus of the Alt lab is the elucidation of mechanisms that generate antigen receptor diversity in the Immune system and mechanisms that maintain... Read more about Frederick W. Alt
We are a collaborative group of genome editing scientists at the Translational Neuroscience Center of Boston Children’s Hospital and Harvard Medical...
Professor of Biological Chemistry and Molecular Pharmacology
Our research focuses on the molecular mechanism of membrane channels, receptors, and transporters. We have been using solution NMR spectroscopy to study...
Gregor Mendel Professor of Genetics and of Medicine
A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA...
Our laboratory is using cellular, molecular, bioengineering, and computational biology tools to understand how mechanical forces generated by the flow of...
Bacterial pathogens that grow within human cells are responsible for multiple diseases and millions of deaths worldwide. The primary goal of our research...
The overarching goal of the Jost lab is to define the molecular mechanisms of host-microbiome communication using a combination of systematic CRISPR...
The Khurana lab uses stem cells, genomic analysis and systems cell biology approaches to better understand and develop patient-specific therapies for...
Our research focuses on the processes that mediate and regulate the movement of membrane proteins throughout cells. In particular our studies have help...
The Lieberman laboratory studies the innate and adaptive immune response to infection and cancer. They seek to understand how cytotoxic T lymphocytes and...
in situ single-cell transcriptomic techniques offer the exciting ability to characterize gene expression within single cells in their native tissue context.... Read more about Jeffrey Moffitt
Though it has historically focused on fundamental biological questions, the Novina lab places a significant emphasis on identifying unmet medical needs...
Elliott T. and Onie H. Adams Professor of Biochemistry and Systems Biology
We seek to use the vast knowledge of biology to predictably design biological systems to enhance our fundamental understanding and to provide solutions...
We are exploring pathogen-host interactions, particularly in the context of animal models relevant to human infection of clinically important enteric...
Our laboratory studies how chromosome behavior and positioning influence genome function and evolution, with implications for gene regulation, genome...