The broad focus of the Alt lab is the elucidation of mechanisms that generate antigen receptor diversity in the Immune system and mechanisms that maintain... Read more about Frederick W. Alt
Our lab’s long-term goal is to create a novel gene therapy-based therapeutic to preserve and restore healthy vision for patients suffering from diseases that... Read more about Ryoji Amamoto
We are a collaborative group of genome editing scientists at the Translational Neuroscience Center of Boston Children’s Hospital and Harvard Medical...
Although numerous eukaryotic genomes have been sequenced, much still remains to be understood about how the genes in those genomes are regulated. The...
The step-by-step differentiation of embryonic cells into different types of neurons lays the foundation for our sensory responses, motor commands, and...
Gregor Mendel Professor of Genetics and of Medicine
A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA...
Recent advances in genomics now make it possible to consider enumerating all of the genetic lesions in specific cancers. High throughput approaches are...
Bacterial pathogens that grow within human cells are responsible for multiple diseases and millions of deaths worldwide. The primary goal of our research...
The Khurana lab uses stem cells, genomic analysis and systems cell biology approaches to better understand and develop patient-specific therapies for...
The Lieberman laboratory studies the innate and adaptive immune response to infection and cancer. They seek to understand how cytotoxic T lymphocytes and...
Though it has historically focused on fundamental biological questions, the Novina lab places a significant emphasis on identifying unmet medical needs...
Professor of Biological Chemistry and Molecular Pharmacology
Research in the Roberts laboratory is centered on kinases, kinase inhibitors, and cancer. We work in a variety of model systems and utilize approaches varying... Read more about Thomas McCoy Roberts
Elliott T. and Onie H. Adams Professor of Biochemistry and Systems Biology
We seek to use the vast knowledge of biology to predictably design biological systems to enhance our fundamental understanding and to provide solutions...
We are exploring pathogen-host interactions, particularly in the context of animal models relevant to human infection of clinically important enteric...
Professor of Biological Chemistry and Molecular Pharmacology
We are interested in how kinases in general, and phosphatidylinositol 3-kinases (PI3K) in particular, control malignant transformation. The work of our...