I am the director of urology research at Boston Children's Hospital and a cell biologist and biochemist by training. Research in my laboratory focuses on...
Professor of Biological Chemistry and Molecular Pharmacology
The Adelman lab aims to elucidate how cells react in a rapid yet balanced manner to external signals, at the transcriptional and epigenetic level. We use...
The Aguayo-Mazzucato Lab is interested in studying the aging process of pancreatic beta cells and how it contributes to the development of diabetes.... Read more about Cristina Aguayo-Mazzucato
Our laboratory at Dana-Farber Cancer Institute is a basic and translational oncology laboratory focused on studying pancreatic cancer and other RAS-driven...
The broad focus of the Alt lab is the elucidation of mechanisms that generate antigen receptor diversity in the Immune system and mechanisms that maintain... Read more about Frederick W. Alt
Our lab’s long-term goal is to create a novel gene therapy-based therapeutic to preserve and restore healthy vision for patients suffering from diseases that... Read more about Ryoji Amamoto
Messenger RNA is in constant flux between different locations and states -- the nucleus and cytoplasm, activation and silencing, translation and decay.... Read more about Paul Joseph Anderson
We are a collaborative group of genome editing scientists at the Translational Neuroscience Center of Boston Children’s Hospital and Harvard Medical...
There is now overwhelming evidence indicating that VEGF, TGFβ, PDGF, and Notch among others, the molecules that are essential for vascular formation, are...
Richard and Susan Smith Distinguished Professor of Medicine
In erythrocytes, Protein 4.1R is essential for membrane integrity. Deficiencies cause congenital hemolytic anemia. We have shown that there are many isoforms... Read more about Edward Benz
Though much of what defines a human is encoded in the sequence of our DNA, many additional factors influence how this genetic information is manifest. For... Read more about Bradley E. Bernstein
My laboratory is focused on endothelial cells and how they become disrupted in disease. We also study a normal, yet highly proliferative endothelial cell...
As a physician-scientist caring for children with chronic disease I am acutely aware of the burden caused by these conditions and the need for improved... Read more about David T. Breault
We are interested in elucidating the cellular processes and pathways that are involved in the initiation and progression of epithelial tumors. Currently...
Assistant Professor of Stem Cell and Regenerative Biology
Our laboratory seeks to advance our understanding of gene regulation biology using single-cell methods. To do this, we develop new technologies that integrate... Read more about Jason Daniel Buenrostro
Although numerous eukaryotic genomes have been sequenced, much still remains to be understood about how the genes in those genomes are regulated. The...