Our laboratory at the Dana-Farber Cancer Institute is focused on mechanistic study of the pathways that underlie cancer initiation, progression, and drug...
Forst Family Professor of Stem Cell and Regenerative Biology
The broad interest of the WAGERS LAB is to identify and analyze tissue-specific stem cell populations in adult animals. This work focuses on understanding...
Our lab is interested in identifying mechanisms that regulate the normal development and function of the human cerebral cortex. The cortex is the largest... Read more about Christopher A. Walsh
Professor of Biological Chemistry and Molecular Pharmacology
We use frog egg extracts to study the molecular mechanisms underlying DNA replication and repair, and how these processes go awry in human disease. We are...
My laboratory’s research focuses on the skeletal system. We employ a “bedside to bench to bedside” approach in order to delineate biologic pathways that...
Dr. Wu's laboratory focuses on dissecting the underlying mechanisms of pathobiology of chronic lymphocytic leukemia (CLL) as a means to more rationally... Read more about Catherine Ju-Ying Wu
Asa and Patricia Springer Professor of Structural Biology, Professor of Biological Chemistry and Molecular Pharmacology
The Wu laboratory of structural immunology focuses on elucidating the molecular mechanism of signal transduction by immune receptors, especially innate...
Our laboratory studies how chromosome behavior and positioning influence genome function and evolution, with implications for gene regulation, genome...
Our lab aims to understand the in vivo functions of certain genes identified in neurodegenerative and developmental disorders of the human brain such as...
Professor of Biological Chemistry and Molecular Pharmacology
We are interested in how kinases in general, and phosphatidylinositol 3-kinases (PI3K) in particular, control malignant transformation. The work of our...
Antibodies, checkpoint inhibitors, and CAR-T cells have all been successful in leveraging the immune system against disease, but these treatment strategies... Read more about Xin Zhou
Maintenance of genomic integrity is essential for the survival of all organisms. In humans, loss of genomic integrity is closely linked to cancers and...
Assistant Professor of Biological Chemistry and Molecular Pharmacology
Our lab studies the molecular mechanisms of sensory transduction, seeking to understand how animals detect the physical and chemical cues from their...
Edward Mallinckrodt Jr. Professor of Immunopathology
We are trying to understand how circulating cells manage to leave the blood stream and home to distinct organs or tissues where they may have crucial...
