Bacterial cells come in a wide variety of shapes and sizes. Within a given class, however, cells typically grow and divide in such a way as to maintain...
Gregor Mendel Professor of Genetics and of Medicine
A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA...
Mice live 3 years, dogs 15 years and humans 100 years. How does Nature change the lifespan of species? We are trying to uncover the molecular basis for...
Our lab focuses on the molecular nature of innate immune interactions between microbial pathogens and the host. Pathogenic bacteria have evolved complex...
Bacterial pathogens that grow within human cells are responsible for multiple diseases and millions of deaths worldwide. The primary goal of our research...
The increasing emergence of bacterial strains resistant to antibiotics is far outpacing our ability to develop novel therapies to treat these infections....
The overarching goal of the Jost lab is to define the molecular mechanisms of host-microbiome communication using a combination of systematic CRISPR...
Ancient signaling pathways lie at the base of the initiation of immunity, serving to transmit signals from Pattern Recognition Receptors (PRRs) to trigger...
Professor of Biological Chemistry and Molecular Pharmacology
For many years our research group has been interested in the molecular mechanisms of various antibiotics and the fundamental cellular processes they inhibit.... Read more about Daniel Kahne
William Ellery Channing Professor of Medicine and Professor of Immunology
My laboratory has long been interested in the interactions of microbes, both commensals and pathogens, with the immune system. Our overall major research...
Our research focuses on the processes that mediate and regulate the movement of membrane proteins throughout cells. In particular our studies have help...
My lab studies the interplay between the gut microbiome and the immune system and how their “miscues” can lead to autoimmune diseases, particularly type 1...
The Lieberman laboratory studies the innate and adaptive immune response to infection and cancer. They seek to understand how cytotoxic T lymphocytes and...
The research efforts in the laboratory are directed towards understanding the molecular basis of pathogenesis of human infections caused by opportunistic...
