Our research focuses on deciphering the molecular mechanisms of metabolic disease and dysfunction, and using this information to develop targeted...

Our lab investigates the metabolic mechanisms that regulate cellular and organismal adaptation to physiologic and pathologic stress conditions. Within...

Our laboratory is studying the regulation, mechanisms, and physiological importance of protein breakdown in animal cells. We are presently attempting to...

The mission of the Greka laboratory is to define fundamental aspects of membrane protein biology and dissect mechanisms of cellular homeostasis. The...

Technology drives biological research. A new technology can instantly provide answers that were difficult or impossible to address using current...

Our laboratory focuses on understanding the role that mitochondria play in mammalian aging and disease. Mitochondria are dynamic organelles that provide...

Ubiquitin and ubiquitin-like (UBL) protein conjugation systems control a vast array of cellular processes, and impact virtually every biological system....

Our laboratory studies how blood platelets, which function as the bandaids of the bloodstream, are produced from megakaryocyte precursor cells....

Our research focuses on the processes that mediate and regulate the movement of membrane proteins throughout cells. In particular our studies have help...

The brain-CSF interface: Neural stem cells and disease

Defined numbers of neural precursor cells are remarkably synchronized in their task to...

Recurrence of cancer in the form of metastatic disease accounts for more than 90% of cancer patient deaths; however, tumor metastasis is considered an...

Though it has historically focused on fundamental biological questions, the Novina lab places a significant emphasis on identifying unmet medical needs...

Our laboratory aims to understand normal cell division mechanisms and to discover cell division defects that are unique to cancer cells. We take a range...

The research interests of the Schwarz lab are centered on the use of genetics to probe the cell biology of the nervous system. We use Drosophila, mouse,...

Using a combination of computational and experimental approaches we study the processes that determine whether mammalian cells live or die. Our lab is...

The major focus of our laboratory is to investigate the cell and molecular biology of cancer, with a focus on the PI 3-Kinase and AKT signaling pathway in...

Our research is focused on the nature of highly aggressive, metastatic, late-stage cancers. We believe that such tumors differ markedly from less...