There is now overwhelming evidence indicating that VEGF, TGFβ, PDGF, and Notch among others, the molecules that are essential for vascular formation, are...
My laboratory is focused on endothelial cells and how they become disrupted in disease. We also study a normal, yet highly proliferative endothelial cell...
Hematopoiesis serves as a useful model system for studies of cell fate determination and lineage plasticity. Lineage-specific transcription factors play...
Professor of Biological Chemistry and Molecular Pharmacology
Our laboratory takes molecular approaches to herpesvirus replication and latency. These studies provide excellent models for biological processes in...
Alvan T. and Viola D. Fuller American Cancer Society Professor of Radiation Oncology
Our laboratory examines the molecular signaling pathways which regulate the DNA damage response in mammalian cells. Disruption of these pathways, by...
Dean of the Faculty of Medicine Caroline Shields Walker Professor of Medicine
Our lab focuses on stem cell biology, with an emphasis on somatic cell reprogramming, hematopoietic differentiation from human and mouse pluripotent stem...
Our group studies cell death/proliferation signals in relation to development and disease, particularly in skin cancer. We attempt to understand critical...
Our laboratory is using cellular, molecular, bioengineering, and computational biology tools to understand how mechanical forces generated by the flow of...
Our laboratory studies diseases of the gastrointestinal tract, with emphasis on colorectal cancer (CRC) and inflammatory bowel disease (IBD). We use both...
Dr. Kaelin's research seeks to understand how, mechanistically, mutations affecting specific genes cause cancer, with a particular focus on particular tumor... Read more about William Kaelin
Neurodegenerative diseases like Alzheimer’s and Parkinson’s disease are diseases caused when proteins abnormally fold and aggregate in specific cell types of... Read more about Vikram Khurana
Our research focuses on the processes that mediate and regulate the movement of membrane proteins throughout cells. In particular our studies have help...
Research in the Levy Lab focuses on endogenous mechanisms for resolution of lung inflammation and injury. The laboratory's overall mission is to identify...
Hersey Professor of the Theory and Practice of Medicine
We are interested in the redox determinants of normal and abnormal blood vessel function and phenotype. Our specific focus has been on nitric oxide as an...
My lab explores signal transduction pathways in the cells and tissues of the cardiovascular system. We have a particular focus on applying biochemical methods... Read more about Thomas M. Michel
Mitochondria are tiny organelles found in nearly all cells, serving as the center stage for ATP production, ion homeostasis, and apoptosis. Their composition,... Read more about Vamsi K. Mootha
The Mullally laboratory is a translational oncology lab focused on the study of myeloid blood cancers, primarily myeloproliferative neoplasms (MPN). We employ... Read more about Ann Mullally
Though it has historically focused on fundamental biological questions, the Novina lab places a significant emphasis on identifying unmet medical needs...
