Although numerous eukaryotic genomes have been sequenced, much still remains to be understood about how the genes in those genomes are regulated. The...

Our group is interested in understanding the structural and biophysical determinants of membrane morphology. Active areas of interest include:...

Diverse control mechanisms converge to ensure that gene transcripts are expressed and processed accurately. Dissection of these interactions has proven...

Research in the Ruvkun lab has explored three major themes: microRNA genes and other small RNAs, control of longevity and immune surveillance, and...

For a living cell to function properly, its cellular processes must be strictly controlled not only in time but also in space. We are interested in how...

My laboratory is interested in the related challenges of understanding the origin of life on the early earth, and constructing synthetic cellular life in...