We use methods in molecular biology, immunology, and structural biology to study host-pathogen interactions, with the goal of informing strategies aimed...
Assistant Professor of Biological Chemistry and Molecular Pharmacology
Protein-Protein Interactions (PPIs) is the Holy Grail of therapeutic intervention, offering a plethora of distinct structural landscapes that can be targeted... Read more about Haribabu Arthanari
Gustavus Adolphus Pfeiffer Professor of Biological Chemistry and Molecular Pharmacology
The long-term goal of our research program is to understand the molecular logic of signal transduction, focusing on proteins implicated in human disease. The... Read more about Stephen Charles Blacklow
Assistant Professor of Biological Chemistry and Molecular Pharmacology
We are interested in understanding transport mechanisms in the cell. In particular, we are interested in how molecules are transported into, out of, and...
Professor of Biological Chemistry and Molecular Pharmacology
Our research focuses on the molecular mechanism of membrane channels, receptors, and transporters. We have been using solution NMR spectroscopy to study...
Diverse control mechanisms converge to ensure that gene transcripts are expressed and processed accurately. Dissection of these interactions has proven...
Professor of Biological Chemistry and Molecular Pharmacology
Our laboratory takes molecular approaches to herpesvirus replication and latency. These studies provide excellent models for biological processes in...
Professor of Medicine Chief, Division of Gastroenterology, Hepatology and Endoscopy
The objective of our research is to understand the molecular and cellular mechanisms whereby intracellular membrane lipid composition regulates lipid and...
Professor of Biological Chemistry and Molecular Pharmacology
We study cell signaling and regulation of the actin cytoskeleton using structural and biochemical approaches. We seek to understand fundamental signaling...
The Farnung Lab aims to answer key mechanistic questions at the intersection of chromatin and transcription. We employ biochemical, biophysical, and structural... Read more about Lucas Farnung
Assistant Professor of Biological Chemistry and Molecular Pharmacology
The Ubiquitin Proteasome System (UPS) is involved in virtually any cellular process and frequently implicated in human pathologies. Ubiquitin, through the... Read more about Eric Fischer
We work on positive strand RNA viruses, with a current focus on understanding how cells sense viral invaders to initiate an immune response. We also have...
Giovanni Armenise - Harvard Professor of Basic Biomedical Science
We are structural biologists concerned with the organization and dynamics of macromolecular assemblies. We ask the following kinds of questions. (1) How...
Our research focuses on the processes that mediate and regulate the movement of membrane proteins throughout cells. In particular our studies have help...
Associate Professor of Biological Chemistry and Molecular Pharmacology
Signal transduction across cell membranes plays a central role in human physiology and disease, yet the mechanistic details underlying transmembrane...
