Organelle structure-function: We investigate how proteins self-organize in the birth, life and death of cellular compartments. Our goal is to understand...
Our goal is to understand the role of neuro-immune interactions in host defense and inflammation. The peripheral nervous system densely innervates barrier...
Diverse control mechanisms converge to ensure that gene transcripts are expressed and processed accurately. Dissection of these interactions has proven...
The Dong laboratory has a broad interest in microbial toxins, bacterial infections, and host-microbe interactions. We are also utilizing toxins as tools...
The Farnung Lab aims to answer key mechanistic questions at the intersection of chromatin and transcription. We employ biochemical, biophysical, and structural... Read more about Lucas Farnung
Assistant Professor of Biological Chemistry and Molecular Pharmacology
The Ubiquitin Proteasome System (UPS) is involved in virtually any cellular process and frequently implicated in human pathologies. Ubiquitin, through the... Read more about Eric Fischer
The mission of the Greka laboratory is to define fundamental aspects of membrane protein biology and dissect mechanisms of cellular homeostasis. The...
Director, Wyss Institute for Biologically Inspired Engineering
My laboratory is interested in how microenvironmental cues, particularly mechanical forces and extracellular matrix, regulate tissue development, physiology... Read more about Donald Elliot Ingber
Our laboratory studies how blood platelets, which function as the bandaids of the bloodstream, are produced from megakaryocyte precursor cells. Megakaryocytes... Read more about Joseph E. Italiano
A. Werk Cook Professor of Radiation Oncology (Tumor Biology)
The overall goal of our research is to understand the role of the tumor microenvironment, including the tumor vasculature and matrix, in tumor growth and...
Our research focuses on the processes that mediate and regulate the movement of membrane proteins throughout cells. In particular our studies have help...
Associate Professor of Biological Chemistry and Molecular Pharmacology
Signal transduction across cell membranes plays a central role in human physiology and disease, yet the mechanistic details underlying transmembrane...
Electron cryo-microscopy (cryo-EM) is a rapidly advancing research area, powered by the knowledge of biology, physics, material science and computation. Single... Read more about Maofu Liao
My lab is interested in the structure, dynamics, and function of the cytoskeleton. We use imaging-based assays in living cells and in vitro extracts, in... Read more about Timothy J. Mitchison
Our laboratory aims to understand normal cell division mechanisms and to discover cell division defects that are unique to cancer cells. We take a range...
We are interested in the development of the vertebrate musculo-skeletal axis. Using chicken and mouse embryos as model systems, we combine developmental... Read more about Olivier Pourquie
