Although numerous eukaryotic genomes have been sequenced, much still remains to be understood about how the genes in those genomes are regulated. The...
Diverse control mechanisms converge to ensure that gene transcripts are expressed and processed accurately. Dissection of these interactions has proven...
We work on positive strand RNA viruses, with a current focus on understanding how cells sense viral invaders to initiate an immune response. We also have...
Director, Wyss Institute for Biologically Inspired Engineering
My laboratory is interested in how microenvironmental cues, particularly mechanical forces and extracellular matrix, regulate tissue development, physiology... Read more about Donald Elliot Ingber
A. Werk Cook Professor of Radiation Oncology (Tumor Biology)
The overall goal of our research is to understand the role of the tumor microenvironment, including the tumor vasculature and matrix, in tumor growth and...