Bacterial cells come in a wide variety of shapes and sizes. Within a given class, however, cells typically grow and divide in such a way as to maintain...
Our goal is to understand the role of neuro-immune interactions in host defense and inflammation. The peripheral nervous system densely innervates barrier...
Gregor Mendel Professor of Genetics and of Medicine
A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA...
Mice live 3 years, dogs 15 years and humans 100 years. How does Nature change the lifespan of species? We are trying to uncover the molecular basis for...
Our lab focuses on the molecular nature of interactions between microbial pathogens and the host. Pathogenic bacteria have evolved complex mechanisms to...
Bacterial pathogens that grow within human cells are responsible for multiple diseases and millions of deaths worldwide. The primary goal of our research...
Director, Wyss Institute for Biologically Inspired Engineering
My laboratory is interested in how microenvironmental cues, particularly mechanical forces and extracellular matrix, regulate tissue development, physiology... Read more about Donald Elliot Ingber
Ancient signaling pathways lie at the base of the initiation of immunity, serving to transmit signals from Pattern Recognition Receptors (PRRs) to trigger...
Professor of Biological Chemistry and Molecular Pharmacology
For many years our research group has been interested in the molecular mechanisms of various antibiotics and the fundamental cellular processes they inhibit.... Read more about Daniel Kahne
Our studies have spanned evolutionarily conserved pathways of innate immunity, the integrative physiology that connects infection and immunity with cellular... Read more about Dennis Kim
Assistant Professor of Biological Chemistry and Molecular Pharmacology
Research in our lab takes a bottom-up approach to tackling molecular challenges in cancer biology. Basic chemical research – development of new reactions,... Read more about Justin Kim
Our research focuses on the processes that mediate and regulate the movement of membrane proteins throughout cells. In particular our studies have help...
My laboratory studies the cell and molecular biology of vesicular transport and a novel mechanism of innate immunity unique to the polarized epithelial...
The Lieberman laboratory studies cytotoxic T lymphocytes and their role in infection and tumor immunity. They study the molecular pathways used by killer...
My lab is interested in the structure, dynamics, and function of the cytoskeleton. We use imaging-based assays in living cells and in vitro extracts, in... Read more about Timothy J. Mitchison
in situ single-cell transcriptomic techniques offer the exciting ability to characterize gene expression within single cells in their native tissue context.... Read more about Jeffrey Moffitt
We are interested in mechanisms whereby bacterial pathogens cause disease and in defining and testing immune protective mechanisms relevant to prevention...
