My lab studies how organisms defend against environmental and metabolic stresses, and how these stress defenses influence aging. Most of our work involves...
Although numerous eukaryotic genomes have been sequenced, much still remains to be understood about how the genes in those genomes are regulated. The...
Hematopoiesis serves as a useful model system for studies of cell fate determination and lineage plasticity. Lineage-specific transcription factors play...
My group is broadly interested in the evolution of transcriptional networks in animals. Whole genome sequence for a wide variety of organisms has shown us...
The step-by-step differentiation of embryonic cells into different types of neurons lays the foundation for our sensory responses, motor commands, and...
Research in our laboratory is committed to expanding our molecular understanding of the formation and regeneration of tendons and ligaments. Injuries to...
Our laboratory seeks to understand the signals that indicate organ injury and regulate growth and regeneration. The inability to recover from acute injury can... Read more about Wolfram Goessling
My lab is interested in how non-genetic information can be transmitted across generations. An increasing number of complex phenotypes, such as physical...
Professor of Biological Chemistry and Molecular Pharmacology
RNA biogenesis and decay mechanisms in stem cells and diseaseOur goal is to understand molecular and cellular mechanisms controlling RNA biogenesis and decay... Read more about Richard I. Gregory
The brain, which represents 2% of the body mass but consumes 20% of the body energy at rest, is therefore highly dependent on oxygen and nutrients supply...
The laboratory studies muscle stem cells in human and mouse tissues, with the goal of developing strategies that will slow the progression of and improve... Read more about Emanuela Gussoni
The focus of this laboratory is to understand the genetic basis of development of form – that is shape, size and proportion during vertebrate development...
Our lab tries to understand the molecular mechanisms underlying pluripotency and nuclear reprogramming. Pluripotency denotes the ability of cells, such as...
Skin, the largest organ we have, protects us from insults and dehydration, and facilitates sensory perception and thermoregulation. These multifaceted...
The Kim Laboratory has pioneered the use of stem cell biology approaches for the study of adult lung progenitor cells and lung cancer. Through a combination of... Read more about Carla Kim
Professor of Biological Chemistry and Molecular Pharmacology
The overarching goal of the Lassar lab is to understand how different cells types (i.e., articular or epiphyseal chondrocytes, ligaments and synoviocytes...
