The broad focus of the Alt lab is the elucidation of mechanisms that generate antigen receptor diversity in the Immune system and mechanisms that maintain... Read more about Frederick W. Alt
Gregor Mendel Professor of Genetics and of Medicine
A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA...
The increasing emergence of bacterial strains resistant to antibiotics is far outpacing our ability to develop novel therapies to treat these infections....
The Mekalanos laboratory is engaged in the analysis of bacterial virulence and functional genomics. The goal of these studies is to understand how pathogenic... Read more about John Joseph Mekalanos
Xander University Professor of Stem Cell and Regenerative Biology
Research in our laboratory focuses on the developmental biology of the pancreas. We wish to understand how the pancreas normally develops and use that... Read more about Douglas A. Melton
Though it has historically focused on fundamental biological questions, the Novina lab places a significant emphasis on identifying unmet medical needs...
The vertebrate immune system is capable of specifically recognizing and responding to an enormous number of antigens. The interaction with antigen is...
Immune-mediated diseases such as lupus or rheumatoid arthritis are not caused by an isolated insult resulting in a single dysfunctional gene or pathway,...
We are exploring pathogen-host interactions, particularly in the context of animal models relevant to human infection of clinically important enteric...
