The broad focus of the Alt lab is the elucidation of mechanisms that generate antigen receptor diversity in the Immune system and mechanisms that maintain... Read more about Frederick W. Alt
Diverse control mechanisms converge to ensure that gene transcripts are expressed and processed accurately. Dissection of these interactions has proven...
My group is broadly interested in the evolution of transcriptional networks in animals. Whole genome sequence for a wide variety of organisms has shown us...
The step-by-step differentiation of embryonic cells into different types of neurons lays the foundation for our sensory responses, motor commands, and...
The human brain is a highly organized structure containing myriad axon tracts that follow precise pathways and make predictable connections, yet only a...
Mice live 3 years, dogs 15 years and humans 100 years. How does Nature change the lifespan of species? We are trying to uncover the molecular basis for...
Our major goal is to understand how lncRNAs interact with chromatin complexes to achieve locus-specific and temporally specific gene expression patterns. We... Read more about Jeannie T. Lee
Our lab is interested in the biologic basis of cardiac and vascular disease. In a multidisciplinary approach to these problems, involving group members who are... Read more about Calum Archibald MacRae
Max and Anne Wien Professor of Stem Cell and Regenerative Biology
Our laboratory is directed toward both 1) understanding molecular controls and mechanisms over neuron sub-type development, diversity, axon guidance-...
The Megason Lab uses imaging-based systems biology to elucidate the systems level principles of animal development. We are particularly interested in long...
We are interested in epigenetic mechanisms that control cellular memory and genome stability in eukaryotes and use yeast and mammalian cells as model...
Though it has historically focused on fundamental biological questions, the Novina lab places a significant emphasis on identifying unmet medical needs...
Our laboratory aims to understand normal cell division mechanisms and to discover cell division defects that are unique to cancer cells. We take a range...
Evelyn and James Jenks and Paul Dudley White Professor of Medicine in the Field of Cardiology
We are interested in why the heart fails. Heart failure is an enormous and growing cause of death and disability throughout the world. In addition, the...
Elliott T. and Onie H. Adams Professor of Biochemistry and Systems Biology
What can we build with biology? We use a synthetic biology approach to understanding biological systems through design, making new biological structures...
My research focuses on understanding the relationship between genotype and phenotype, with a special interest in how biochemistry, molecular design, and...
We are exploring pathogen-host interactions, particularly in the context of animal models relevant to human infection of clinically important enteric...
