Professor of Biological Chemistry and Molecular Pharmacology
The Adelman lab aims to elucidate how cells react in a rapid yet balanced manner to external signals, at the transcriptional and epigenetic level. We use...
The broad focus of the Alt lab is the elucidation of mechanisms that generate antigen receptor diversity in the Immune system and mechanisms that maintain... Read more about Frederick W. Alt
Professor of Biological Chemistry and Molecular Pharmacology
The bithorax complex in the fruit fly is a cluster of “homeotic” genes which confer distinct identities on the different segments of the fly. The genes...
Though much of what defines a human is encoded in the sequence of our DNA, many additional factors influence how this genetic information is manifest. For... Read more about Bradley E. Bernstein
My lab studies how organisms defend against environmental and metabolic stresses, and how these stress defenses influence aging. Most of our work involves...
We are interested in elucidating the cellular processes and pathways that are involved in the initiation and progression of epithelial tumors. Currently...
Although numerous eukaryotic genomes have been sequenced, much still remains to be understood about how the genes in those genomes are regulated. The...
Hematopoiesis serves as a useful model system for studies of cell fate determination and lineage plasticity. Lineage-specific transcription factors play...
Assistant Professor of Stem Cell and Regenerative Biology
Cells in complex mammalian tissues, such as the brain, are spatially organized and dynamic, yet almost all genomic tools lack temporal and spatial resolution.... Read more about Fei Chen
Dr. Chen's group has developed a number of novel conditional mouse strains that have aided in their detailed characterization and elucidation of the...
The D'Amore laboratory has a long-standing interest in the regulation of vascular development and pathology. One major area has involved investigating the role... Read more about Patricia Ann D'Amore
Dean of the Faculty of Medicine Caroline Shields Walker Professor of Medicine
Our lab focuses on stem cell biology, with an emphasis on somatic cell reprogramming, hematopoietic differentiation from human and mouse pluripotent stem...
My group is broadly interested in the evolution of transcriptional networks in animals. Whole genome sequence for a wide variety of organisms has shown us...
Our broad interest is to understand how cell-cell signaling molecules set up spatial pattern, particularly in the formation of neuronal connections. We...
The brain, which represents 2% of the body mass but consumes 20% of the body energy at rest, is therefore highly dependent on oxygen and nutrients supply...
Kurt J. Isselbacher/Peter D. Schwartz Professor of Oncology
Our laboratory is interested in the genetics of human cancer. Current projects include the use of a microfluidic device to capture circulating tumor cells...
