Although numerous eukaryotic genomes have been sequenced, much still remains to be understood about how the genes in those genomes are regulated. The...
Diverse control mechanisms converge to ensure that gene transcripts are expressed and processed accurately. Dissection of these interactions has proven...
Gregor Mendel Professor of Genetics and of Medicine
A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA...
Neurodegenerative diseases like Alzheimer’s and Parkinson’s disease are diseases caused when proteins abnormally fold and aggregate in specific cell types of... Read more about Vikram Khurana
Elliott T. and Onie H. Adams Professor of Biochemistry and Systems Biology
What can we build with biology? We use a synthetic biology approach to understanding biological systems through design, making new biological structures...
My research focuses on understanding the relationship between genotype and phenotype, with a special interest in how biochemistry, molecular design, and...
Professor of Biological Chemistry and Molecular Pharmacology
We are interested in how kinases in general, and phosphatidylinositol 3-kinases (PI3K) in particular, control malignant transformation. The work of our...