The broad focus of the Alt lab is the elucidation of mechanisms that generate antigen receptor diversity in the Immune system and mechanisms that maintain... Read more about Frederick W. Alt
Although numerous eukaryotic genomes have been sequenced, much still remains to be understood about how the genes in those genomes are regulated. The...
Diverse control mechanisms converge to ensure that gene transcripts are expressed and processed accurately. Dissection of these interactions has proven...
The step-by-step differentiation of embryonic cells into different types of neurons lays the foundation for our sensory responses, motor commands, and...
Gregor Mendel Professor of Genetics and of Medicine
A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA...
Recent advances in genomics now make it possible to consider enumerating all of the genetic lesions in specific cancers. High throughput approaches are...
Neurodegenerative diseases like Alzheimer’s and Parkinson’s disease are diseases caused when proteins abnormally fold and aggregate in specific cell types of... Read more about Vikram Khurana
Dorothy and Milton Flier Professor of Biomedical Science and Genetics
We are working to understand (i) how the human genome varies from person to person, and (ii) how inherited genome variation affects the biology of neurons...
The Megason Lab uses imaging-based systems biology to elucidate the systems level principles of animal development. We are particularly interested in long...
Though it has historically focused on fundamental biological questions, the Novina lab places a significant emphasis on identifying unmet medical needs...
Elliott T. and Onie H. Adams Professor of Biochemistry and Systems Biology
What can we build with biology? We use a synthetic biology approach to understanding biological systems through design, making new biological structures...
My research focuses on understanding the relationship between genotype and phenotype, with a special interest in how biochemistry, molecular design, and...
We are exploring pathogen-host interactions, particularly in the context of animal models relevant to human infection of clinically important enteric...
Professor of Biological Chemistry and Molecular Pharmacology
We are interested in how kinases in general, and phosphatidylinositol 3-kinases (PI3K) in particular, control malignant transformation. The work of our...
