A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA...

The overarching goal of the Jost lab is to define the molecular mechanisms of host-microbiome communication using a combination of systematic CRISPR...

What can we build with biology? We use a synthetic biology approach to understanding biological systems through design, making new biological structures...

We are exploring pathogen-host interactions, particularly in the context of animal models relevant to human infection of clinically important enteric...