I am the director of urology research at Boston Children's Hospital and a cell biologist and biochemist by training. Research in my laboratory focuses on...
The Aguayo-Mazzucato Lab is interested in studying the aging process of pancreatic beta cells and how it contributes to the development of diabetes.... Read more about Cristina Aguayo-Mazzucato
Messenger RNA is in constant flux between different locations and states -- the nucleus and cytoplasm, activation and silencing, translation and decay.... Read more about Paul Joseph Anderson
Richard and Susan Smith Distinguished Professor of Medicine
In erythrocytes, Protein 4.1R is essential for membrane integrity. Deficiencies cause congenital hemolytic anemia. We have shown that there are many isoforms... Read more about Edward Benz
Though much of what defines a human is encoded in the sequence of our DNA, many additional factors influence how this genetic information is manifest. For... Read more about Bradley E. Bernstein
My laboratory is focused on endothelial cells and how they become disrupted in disease. We also study a normal, yet highly proliferative endothelial cell...
As a physician-scientist caring for children with chronic disease I am acutely aware of the burden caused by these conditions and the need for improved... Read more about David T. Breault
We are interested in elucidating the cellular processes and pathways that are involved in the initiation and progression of epithelial tumors. Currently...
My laboratory is interested in mechanisms and therapy of cancers. In the past years, I have been working on different types of hematologic and solid...
The focus of my laboratory is to elucidate how deregulated cell signaling drives cancer. To achieve this we have been taking a multi-faceted approach;...
Professor of Biological Chemistry and Molecular Pharmacology
Our laboratory takes molecular approaches to herpesvirus replication and latency. These studies provide excellent models for biological processes in...
Professor of Medicine Chief, Division of Gastroenterology, Hepatology and Endoscopy
The objective of our research is to understand the molecular and cellular mechanisms whereby intracellular membrane lipid composition regulates lipid and...
The D'Amore laboratory has a long-standing interest in the regulation of vascular development and pathology. One major area has involved investigating the role... Read more about Patricia Ann D'Amore
Alvan T. and Viola D. Fuller American Cancer Society Professor of Radiation Oncology
Our laboratory examines the molecular signaling pathways which regulate the DNA damage response in mammalian cells. Disruption of these pathways, by...
Dean of the Faculty of Medicine Caroline Shields Walker Professor of Medicine
Our lab focuses on stem cell biology, with an emphasis on somatic cell reprogramming, hematopoietic differentiation from human and mouse pluripotent stem...
Dr. Daly's lab focuses on computational approaches to understanding the genetics of disease with a strategy of integrating powerful techniques from human...
Our lab investigates the metabolic mechanisms that regulate cellular and organismal adaptation to physiologic and pathologic stress conditions. Within...