Professor of Biological Chemistry and Molecular Pharmacology
The Adelman lab aims to elucidate how cells react in a rapid yet balanced manner to external signals, at the transcriptional and epigenetic level. We use...
Our laboratory at Dana-Farber Cancer Institute is a basic and translational oncology laboratory focused on studying pancreatic cancer and other RAS-driven...
The broad focus of the Alt lab is the elucidation of mechanisms that generate antigen receptor diversity in the Immune system and mechanisms that maintain... Read more about Frederick W. Alt
There is now overwhelming evidence indicating that VEGF, TGFβ, PDGF, and Notch among others, the molecules that are essential for vascular formation, are...
Although numerous eukaryotic genomes have been sequenced, much still remains to be understood about how the genes in those genomes are regulated. The...
The Ebert laboratory focuses on the molecular basis and treatment of hematologic malignancies, with a particular focus on myelodysplastic syndromes (MDS...
Gregor Mendel Professor of Genetics and of Medicine
A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA...
Bullard Professor of Neurogenetics in the Department of Genetics
My laboratory is focused on understanding nervous system disease using molecular genetic strategies, beginning with human patients and proceeding through...
The Hacohen lab consists of immunologists, geneticists, biochemists, technologists, physicians and computational biologists working together to develop...
Recent advances in genomics now make it possible to consider enumerating all of the genetic lesions in specific cancers. High throughput approaches are...
The long-term goal of my laboratory is to identify and evaluate genetic determinants underlying inherited retinal diseases and develop appropriate therapeutic... Read more about Neena B. Haider
Our laboratory studies diseases of the gastrointestinal tract, with emphasis on colorectal cancer (CRC) and inflammatory bowel disease (IBD). We use both...
Our laboratory focuses on understanding the role that mitochondria play in mammalian aging and disease. Mitochondria are dynamic organelles that provide...
My laboratory is focused on two tumor suppressor gene diseases associated with renal tumorigenesis and hamartomas: tuberous sclerosis complex (TSC) and...
Skin, the largest organ we have, protects us from insults and dehydration, and facilitates sensory perception and thermoregulation. These multifaceted...
The increasing emergence of bacterial strains resistant to antibiotics is far outpacing our ability to develop novel therapies to treat these infections....
Neurodegenerative diseases like Alzheimer’s and Parkinson’s disease are diseases caused when proteins abnormally fold and aggregate in specific cell types of... Read more about Vikram Khurana
