Though much of what defines a human is encoded in the sequence of our DNA, many additional factors influence how this genetic information is manifest. For... Read more about Bradley E. Bernstein
My laboratory is focused on endothelial cells and how they become disrupted in disease. We also study a normal, yet highly proliferative endothelial cell...
The D'Amore laboratory has a long-standing interest in the regulation of vascular development and pathology. One major area has involved investigating the role... Read more about Patricia Ann D'Amore
Alvan T. and Viola D. Fuller American Cancer Society Professor of Radiation Oncology
Our laboratory examines the molecular signaling pathways which regulate the DNA damage response in mammalian cells. Disruption of these pathways, by...
Dean of the Faculty of Medicine Caroline Shields Walker Professor of Medicine
Our lab focuses on stem cell biology, with an emphasis on somatic cell reprogramming, hematopoietic differentiation from human and mouse pluripotent stem...
Recent advances in genomics now make it possible to consider enumerating all of the genetic lesions in specific cancers. High throughput approaches are...
My laboratory is focused on two tumor suppressor gene diseases associated with renal tumorigenesis and hamartomas: tuberous sclerosis complex (TSC) and...
Director, Wyss Institute for Biologically Inspired Engineering
My laboratory is interested in how microenvironmental cues, particularly mechanical forces and extracellular matrix, regulate tissue development, physiology... Read more about Donald Elliot Ingber
A. Werk Cook Professor of Radiation Oncology (Tumor Biology)
The overall goal of our research is to understand the role of the tumor microenvironment, including the tumor vasculature and matrix, in tumor growth and...
Dr. Kaelin's research seeks to understand how, mechanistically, mutations affecting specific genes cause cancer, with a particular focus on particular tumor... Read more about William Kaelin
Hersey Professor of the Theory and Practice of Medicine
We are interested in the redox determinants of normal and abnormal blood vessel function and phenotype. Our specific focus has been on nitric oxide as an...
The vast array of forms and functions exhibited by different cell types is made possible by the organization of specialized domains within the cell cortex...
Though it has historically focused on fundamental biological questions, the Novina lab places a significant emphasis on identifying unmet medical needs...
Professor of Biological Chemistry and Molecular Pharmacology
Research in the Roberts laboratory is centered on kinases, kinase inhibitors, and cancer. We work in a variety of model systems and utilize approaches varying... Read more about Thomas McCoy Roberts
My laboratory studies the biology of the adipocyte, with specific emphasis on deciphering the transcriptional pathways that promote adipogenesis and regulate... Read more about Evan D. Rosen
Evelyn and James Jenks and Paul Dudley White Professor of Medicine in the Field of Cardiology
We are interested in why the heart fails. Heart failure is an enormous and growing cause of death and disability throughout the world. In addition, the...
