The broad focus of the Alt lab is the elucidation of mechanisms that generate antigen receptor diversity in the Immune system and mechanisms that maintain... Read more about Frederick W. Alt
Though much of what defines a human is encoded in the sequence of our DNA, many additional factors influence how this genetic information is manifest. For... Read more about Bradley E. Bernstein
Gregor Mendel Professor of Genetics and of Medicine
A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA...
Our broad interest is to understand how cell-cell signaling molecules set up spatial pattern, particularly in the formation of neuronal connections. We...
Bullard Professor of Neurogenetics in the Department of Genetics
My laboratory is focused on understanding nervous system disease using molecular genetic strategies, beginning with human patients and proceeding through...
Recent advances in genomics now make it possible to consider enumerating all of the genetic lesions in specific cancers. High throughput approaches are...
Our laboratory focuses on understanding the role that mitochondria play in mammalian aging and disease. Mitochondria are dynamic organelles that provide...
My laboratory is focused on two tumor suppressor gene diseases associated with renal tumorigenesis and hamartomas: tuberous sclerosis complex (TSC) and...
Our major goal is to understand how lncRNAs interact with chromatin complexes to achieve locus-specific and temporally specific gene expression patterns. We... Read more about Jeannie T. Lee
Max and Anne Wien Professor of Stem Cell and Regenerative Biology
Our laboratory is directed toward both 1) understanding molecular controls and mechanisms over neuron sub-type development, diversity, axon guidance-...
We are interested in epigenetic mechanisms that control cellular memory and genome stability in eukaryotes and use yeast and mammalian cells as model...
Though it has historically focused on fundamental biological questions, the Novina lab places a significant emphasis on identifying unmet medical needs...
Our laboratory aims to understand normal cell division mechanisms and to discover cell division defects that are unique to cancer cells. We take a range...
My laboratory studies the biology of the adipocyte, with specific emphasis on deciphering the transcriptional pathways that promote adipogenesis and regulate... Read more about Evan D. Rosen
Evelyn and James Jenks and Paul Dudley White Professor of Medicine in the Field of Cardiology
We are interested in why the heart fails. Heart failure is an enormous and growing cause of death and disability throughout the world. In addition, the...
Elliott T. and Onie H. Adams Professor of Biochemistry and Systems Biology
What can we build with biology? We use a synthetic biology approach to understanding biological systems through design, making new biological structures...
