The broad focus of the Alt lab is the elucidation of mechanisms that generate antigen receptor diversity in the Immune system and mechanisms that maintain... Read more about Frederick W. Alt
Gregor Mendel Professor of Genetics and of Medicine
A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA...
Mice live 3 years, dogs 15 years and humans 100 years. How does Nature change the lifespan of species? We are trying to uncover the molecular basis for...
Bullard Professor of Neurogenetics in the Department of Genetics
My laboratory is focused on understanding nervous system disease using molecular genetic strategies, beginning with human patients and proceeding through...
Recent advances in genomics now make it possible to consider enumerating all of the genetic lesions in specific cancers. High throughput approaches are...
Our laboratory focuses on understanding the role that mitochondria play in mammalian aging and disease. Mitochondria are dynamic organelles that provide...
The focus of this laboratory is to understand the genetic basis of development of form – that is shape, size and proportion during vertebrate development...
My laboratory is focused on two tumor suppressor gene diseases associated with renal tumorigenesis and hamartomas: tuberous sclerosis complex (TSC) and...
Our major goal is to understand how lncRNAs interact with chromatin complexes to achieve locus-specific and temporally specific gene expression patterns. We... Read more about Jeannie T. Lee
Max and Anne Wien Professor of Stem Cell and Regenerative Biology
Our laboratory is directed toward both 1) understanding molecular controls and mechanisms over neuron sub-type development, diversity, axon guidance-...
Xander University Professor of Stem Cell and Regenerative Biology
Research in our laboratory focuses on the developmental biology of the pancreas. We wish to understand how the pancreas normally develops and use that... Read more about Douglas A. Melton
We are interested in epigenetic mechanisms that control cellular memory and genome stability in eukaryotes and use yeast and mammalian cells as model...
Though it has historically focused on fundamental biological questions, the Novina lab places a significant emphasis on identifying unmet medical needs...
Our laboratory aims to understand normal cell division mechanisms and to discover cell division defects that are unique to cancer cells. We take a range...
Evelyn and James Jenks and Paul Dudley White Professor of Medicine in the Field of Cardiology
We are interested in why the heart fails. Heart failure is an enormous and growing cause of death and disability throughout the world. In addition, the...
Elliott T. and Onie H. Adams Professor of Biochemistry and Systems Biology
What can we build with biology? We use a synthetic biology approach to understanding biological systems through design, making new biological structures...
