A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA...

Mice live 3 years, dogs 15 years and humans 100 years. How does Nature change the lifespan of species? We are trying to uncover the molecular basis for...

Technology drives biological research. A new technology can instantly provide answers that were difficult or impossible to address using current...

Research in our laboratory is focused on understanding how bacterial pathogens co-opt eukaryotic host cell processes to promote infection and cause...

We are interested in epigenetic mechanisms that control cellular memory and genome stability in eukaryotes and use yeast and mammalian cells as model...

Our laboratory aims to understand normal cell division mechanisms and to discover cell division defects that are unique to cancer cells. We take a range...

What can we build with biology? We use a synthetic biology approach to understanding biological systems through design, making new biological structures...

We are interested in how kinases in general, and phosphatidylinositol 3-kinases (PI3K) in particular, control malignant transformation. The work of our...