Professor of Biological Chemistry and Molecular Pharmacology
The Adelman lab aims to elucidate how cells react in a rapid yet balanced manner to external signals, at the transcriptional and epigenetic level. We use...
We are a collaborative group of genome editing scientists at the Translational Neuroscience Center of Boston Children’s Hospital and Harvard Medical...
Associate Professor of Biological Chemistry and Molecular Pharmacology
Protein-Protein Interactions (PPIs) is the Holy Grail of therapeutic intervention, offering a plethora of distinct structural landscapes that can be targeted... Read more about Haribabu Arthanari
Gustavus Adolphus Pfeiffer Professor of Biological Chemistry and Molecular Pharmacology
The long-term goal of our research program is to understand the molecular logic of signal transduction, focusing on proteins implicated in human disease. The... Read more about Stephen Charles Blacklow
Associate Professor of Biological Chemistry and Molecular Pharmacology
We are interested in understanding transport mechanisms in the cell. In particular, we are interested in how molecules are transported into, out of, and...
Professor of Biological Chemistry and Molecular Pharmacology
Our lab studies eukaryotic gene expression. We are concentrating on three areas: (A) the functions and interactions of the RNA polymerase II (RNApII)...
Hematopoiesis serves as a useful model system for studies of cell fate determination and lineage plasticity. Lineage-specific transcription factors play...
Professor of Biological Chemistry and Molecular Pharmacology
Our laboratory takes molecular approaches to herpesvirus replication and latency. These studies provide excellent models for biological processes in...
Alvan T. and Viola D. Fuller American Cancer Society Professor of Radiation Oncology
Our laboratory examines the molecular signaling pathways which regulate the DNA damage response in mammalian cells. Disruption of these pathways, by...
Dean of the Faculty of Medicine Caroline Shields Walker Professor of Medicine
Our lab focuses on stem cell biology, with an emphasis on somatic cell reprogramming, hematopoietic differentiation from human and mouse pluripotent stem...
Associate Professor of Biological Chemistry and Molecular Pharmacology
The Ubiquitin Proteasome System (UPS) is involved in virtually any cellular process and frequently implicated in human pathologies. Ubiquitin, through the...
Professor of Biological Chemistry and Molecular Pharmacology
RNA biogenesis and decay mechanisms in stem cells and diseaseOur goal is to understand molecular and cellular mechanisms controlling RNA biogenesis and decay... Read more about Richard I. Gregory
Associate Professor, Department of Pediatric Oncology
Our laboratory research program is centered in understanding the structure and function of ATP-dependent chromatin remodeling complexes, with emphasis on...
Professor of Biological Chemistry and Molecular Pharmacology
For many years our research group has been interested in the molecular mechanisms of various antibiotics and the fundamental cellular processes they inhibit.... Read more about Daniel Kahne
Our current research includes three themes. First, we are studying the role of non-canonical nucleic acid structures, G-quadruplex (G4) and R-loop in...