Gustavus Adolphus Pfeiffer Professor of Biological Chemistry and Molecular Pharmacology
The long-term goal of our research program is to understand the molecular logic of signal transduction, focusing on proteins implicated in human disease. The... Read more about Stephen Charles Blacklow
Assistant Professor of Biological Chemistry and Molecular Pharmacology
We are interested in understanding transport mechanisms in the cell. In particular, we are interested in how molecules are transported into, out of, and...
Our research focuses on new technologies for genomic & proteomic measurement, synthesis and modeling of biomedical & ecological systems -- in... Read more about George Mcdonald Church
Professor of Medicine Chief, Division of Gastroenterology, Hepatology and Endoscopy
The objective of our research is to understand the molecular and cellular mechanisms whereby intracellular membrane lipid composition regulates lipid and...
Assistant Professor of Biological Chemistry and Molecular Pharmacology
We are not alone. The human body harbors more bacterial cells than human cells, and approximately one kilogram of bacteria reside in the human gut. From...
Gregor Mendel Professor of Genetics and of Medicine
A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA...
Mice live 3 years, dogs 15 years and humans 100 years. How does Nature change the lifespan of species? We are trying to uncover the molecular basis for...
Our laboratory is studying the regulation, mechanisms, and physiological importance of protein breakdown in animal cells. We are presently attempting to...
Our lab focuses on the molecular nature of interactions between microbial pathogens and the host. Pathogenic bacteria have evolved complex mechanisms to...
Bacterial pathogens that grow within human cells are responsible for multiple diseases and millions of deaths worldwide. The primary goal of our research...
The overarching goal of the Jost lab is to define the molecular mechanisms of host-microbiome communication using a combination of systematic CRISPR...
William Ellery Channing Professor of Medicine and Professor of Immunology
My laboratory has long been interested in the interactions of microbes, both commensals and pathogens, with the immune system. Our overall major research...
Our research focuses on the processes that mediate and regulate the movement of membrane proteins throughout cells. In particular our studies have help...
The ability to precisely and permanently alter DNA sequences in living cells has been dramatically simplified by the adaptation of a prokaryotic immune...
My lab studies the interplay between the gut microbiome and the immune system and how their “miscues” can lead to autoimmune diseases, particularly type 1...
The Lieberman laboratory studies cytotoxic T lymphocytes and their role in infection and tumor immunity. They study the molecular pathways used by killer...
