Our laboratory at Dana-Farber Cancer Institute is a basic and translational oncology laboratory focused on studying pancreatic cancer and other RAS-driven...
Though much of what defines a human is encoded in the sequence of our DNA, many additional factors influence how this genetic information is manifest. For... Read more about Bradley E. Bernstein
Although numerous eukaryotic genomes have been sequenced, much still remains to be understood about how the genes in those genomes are regulated. The...
Assistant Professor of Stem Cell and Regenerative Biology
Cells in complex mammalian tissues, such as the brain, are spatially organized and dynamic, yet almost all genomic tools lack temporal and spatial resolution.... Read more about Fei Chen
Diverse control mechanisms converge to ensure that gene transcripts are expressed and processed accurately. Dissection of these interactions has proven...
The Ebert laboratory focuses on the molecular basis and treatment of hematologic malignancies, with a particular focus on myelodysplastic syndromes (MDS...
Bullard Professor of Neurogenetics in the Department of Genetics
My laboratory is focused on understanding nervous system disease using molecular genetic strategies, beginning with human patients and proceeding through...
The Hacohen lab consists of immunologists, geneticists, biochemists, technologists, physicians and computational biologists working together to develop...
Our laboratory studies diseases of the gastrointestinal tract, with emphasis on colorectal cancer (CRC) and inflammatory bowel disease (IBD). We use both...
Neurodegenerative diseases like Alzheimer’s and Parkinson’s disease are diseases caused when proteins abnormally fold and aggregate in specific cell types of... Read more about Vikram Khurana
Our lab studies how individual cells translate internal and external signals into decisions such as growth, death, movement or differentiation. We... Read more about Galit Lahav
The human brain—and the diseases that afflict it—present unique challenges for experimental study, chief among them being tissue availability (only at...
Dorothy and Milton Flier Professor of Biomedical Science and Genetics
We are working to understand (i) how the human genome varies from person to person, and (ii) how inherited genome variation affects the biology of neurons...
Though it has historically focused on fundamental biological questions, the Novina lab places a significant emphasis on identifying unmet medical needs...
The vertebrate immune system is capable of specifically recognizing and responding to an enormous number of antigens. The interaction with antigen is...
Our laboratory utilizes human genetic approaches to gain insight into blood cell production (hematopoiesis) and how this process is perturbed in disease states... Read more about Vijay G. Sankaran
Elliott T. and Onie H. Adams Professor of Biochemistry and Systems Biology
What can we build with biology? We use a synthetic biology approach to understanding biological systems through design, making new biological structures...
Our laboratory studies how chromosome behavior and positioning influence genome function and evolution, with implications for gene regulation, genome...
