Assistant Professor of Biological Chemistry and Molecular Pharmacology
We are interested in understanding transport mechanisms in the cell. In particular, we are interested in how molecules are transported into, out of, and...
The primarily focus of the work in my laboratory is the molecular understanding of the action of steroid hormone receptors and their role in human cancer. We... Read more about Myles Brown
Assistant Professor of Stem Cell and Regenerative Biology
Our laboratory seeks to advance our understanding of gene regulation biology using single-cell methods. To do this, we develop new technologies that integrate... Read more about Jason Daniel Buenrostro
Assistant Professor of Biological Chemistry and Molecular Pharmacology
Dysregulation of protein homeostasis drives many types of cancer, infection and neurodegeneration. The ubiquitin system performs a central role in maintenance... Read more about Sara Buhrlage
Although numerous eukaryotic genomes have been sequenced, much still remains to be understood about how the genes in those genomes are regulated. The...
Professor of Biological Chemistry and Molecular Pharmacology
Our lab studies eukaryotic gene expression. We are concentrating on three areas: (A) the functions and interactions of the RNA polymerase II (RNApII)...
Research in the Burns Laboratory is devoted to understanding how cardiovascular progenitor cells build the vertebrate heart during embryonic development...
Hematopoiesis serves as a useful model system for studies of cell fate determination and lineage plasticity. Lineage-specific transcription factors play...
The B cell receptor (BCR) is essential for survival of mature B cells and its specificity dictates the cells' fate from early development through final...
Assistant Professor of Stem Cell and Regenerative Biology
Cells in complex mammalian tissues, such as the brain, are spatially organized and dynamic, yet almost all genomic tools lack temporal and spatial resolution.... Read more about Fei Chen
Dr. Chen's group has developed a number of novel conditional mouse strains that have aided in their detailed characterization and elucidation of the...
Professor of Biological Chemistry and Molecular Pharmacology
Our research focuses on the molecular mechanism of membrane channels, receptors, and transporters. We have been using solution NMR spectroscopy to study...
Diverse control mechanisms converge to ensure that gene transcripts are expressed and processed accurately. Dissection of these interactions has proven...
The focus of my laboratory is to elucidate how deregulated cell signaling drives cancer. To achieve this we have been taking a multi-faceted approach;...
Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology
The laboratory focuses on understanding how small molecules, particularly those from bacteria and fungi, control biological processes. Organizing themes...
Professor of Biological Chemistry and Molecular Pharmacology
Our laboratory takes molecular approaches to herpesvirus replication and latency. These studies provide excellent models for biological processes in...