Our lab investigates the metabolic mechanisms that regulate cellular and organismal adaptation to physiologic and pathologic stress conditions. Within...
The goal of my lab is to understand the regulatory relationship between cellular signaling pathways and metabolic pathways. We are particularly interested in... Read more about Christian Dibble
Gregor Mendel Professor of Genetics and of Medicine
A major area of our interest is how eukaryotic cells sense and respond to stress in the form of damage to their genetic material. When cells incur DNA...
The Farnung Lab aims to answer key mechanistic questions at the intersection of chromatin and transcription. We employ biochemical, biophysical, and structural... Read more about Lucas Farnung
The molecular mechanisms underlying neurodegeneration in human disorders like Alzheimer's disease and Parkinson's disease remain mysterious, in part...
Assistant Professor of Biological Chemistry and Molecular Pharmacology
The Ubiquitin Proteasome System (UPS) is involved in virtually any cellular process and frequently implicated in human pathologies. Ubiquitin, through the... Read more about Eric Fischer
Our group studies cell death/proliferation signals in relation to development and disease, particularly in skin cancer. We attempt to understand critical...
Our laboratory is using cellular, molecular, bioengineering, and computational biology tools to understand how mechanical forces generated by the flow of...
Mice live 3 years, dogs 15 years and humans 100 years. How does Nature change the lifespan of species? We are trying to uncover the molecular basis for...
Our lab focuses on the molecular nature of innate immune interactions between microbial pathogens and the host. Pathogenic bacteria have evolved complex...
My lab is interested in how non-genetic information can be transmitted across generations. An increasing number of complex phenotypes, such as physical...
The mission of the Greka laboratory is to define fundamental aspects of membrane protein biology and dissect mechanisms of cellular homeostasis. The...
Bullard Professor of Neurogenetics in the Department of Genetics
My laboratory is focused on understanding nervous system disease using molecular genetic strategies, beginning with human patients and proceeding through...
The laboratory studies muscle stem cells in human and mouse tissues, with the goal of developing strategies that will slow the progression of and improve... Read more about Emanuela Gussoni
Kurt J. Isselbacher/Peter D. Schwartz Professor of Oncology
Our laboratory is interested in the genetics of human cancer. Current projects include the use of a microfluidic device to capture circulating tumor cells...
