Our goal is to identify differences between normal and cancerous breast tissue, determine their consequences, and use this information to improve the...
Immune-mediated diseases such as lupus or rheumatoid arthritis are not caused by an isolated insult resulting in a single dysfunctional gene or pathway,...
I do theoretical and experimental work in human population genetics and genomics. The field is moving quickly right now thanks to new genomic technologies...
Our laboratory utilizes human genetic approaches to gain insight into blood cell production (hematopoiesis) and how this process is perturbed in disease states... Read more about Vijay G. Sankaran
The Seidman laboratory uses genetic techniques to study the molecular basis of inherited human disorders. A central project in the laboratory has been to...
Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics
Work in the Seidman laboratory (Dept of Genetics, HMS) is directed toward identifying gene defects that cause inherited heart disease and defining the...
Our laboratory studies the cellular and molecular mechanisms underlying plant responses to central growth and developmental regulators, such as glucose, energy... Read more about Jen Sheen
Our laboratory studies molecular control of development and cell differentiation using self-renewing epithelia in the digestive tract as a model system...
Why do we grow old? Why does aging cause disease? Can we slow aging or even reverse it? These are some of the greatest unsolved questions in biology....
George Jacob and Jacqueline Hazel Leder Professor of Genetics
The laboratory studies the genetic basis by which form and structure are regulated during vertebrate development. In this work, we combine classical...
Within cells macromolecules form complex intertwined networks of functionally interacting components. The molecular mechanisms underlying biological...
Our laboratory at the Dana-Farber Cancer Institute is focused on mechanistic study of the pathways that underlie cancer initiation, progression, and drug...
Our lab is interested in identifying mechanisms that regulate the normal development and function of the human cerebral cortex. The cortex is the largest... Read more about Christopher A. Walsh
My laboratory’s research focuses on the skeletal system. We employ a “bedside to bench to bedside” approach in order to delineate biologic pathways that...
A critical step in eukaryotic gene regulation is the control of transcription across the chromatin template. While transcription has been extensively...
