My laboratory is focused on two tumor suppressor gene diseases associated with renal tumorigenesis and hamartomas: tuberous sclerosis complex (TSC) and...
Bacterial pathogens that grow within human cells are responsible for multiple diseases and millions of deaths worldwide. The primary goal of our research...
Our lab tries to understand the molecular mechanisms underlying pluripotency and nuclear reprogramming. Pluripotency denotes the ability of cells, such as...
Director, Wyss Institute for Biologically Inspired Engineering
My laboratory is interested in how microenvironmental cues, particularly mechanical forces and extracellular matrix, regulate tissue development, physiology... Read more about Donald Elliot Ingber
A. Werk Cook Professor of Radiation Oncology (Tumor Biology)
The overall goal of our research is to understand the role of the tumor microenvironment, including the tumor vasculature and matrix, in tumor growth and...
Dr. Kaelin's research seeks to understand how, mechanistically, mutations affecting specific genes cause cancer, with a particular focus on particular tumor... Read more about William Kaelin
Our laboratory at the Center for Life Sciences is interested in understanding the heterotypic crosstalk that operates between the epithelial and the stromal... Read more about Antoine E. Karnoub
William Ellery Channing Professor of Medicine and Professor of Immunology
My laboratory has long been interested in the interactions of microbes, both commensals and pathogens, with the immune system. Our overall major research...
The Kim Laboratory has pioneered the use of stem cell biology approaches for the study of adult lung progenitor cells and lung cancer. Through a combination of... Read more about Carla Kim
Our research focuses on the processes that mediate and regulate the movement of membrane proteins throughout cells. In particular our studies have help...
Program Head, PhD Program in Virology Professor of Microbiology he/him/his
Our laboratory studies the mechanisms of epigenetic regulation of DNA virus infection. We are interested in the mechanisms by which human cells sense...
The muscular dystrophies are progressive disorders of striated muscle leading to breakdown of muscle integrity. There is considerable clinical variability...
Professor of Biological Chemistry and Molecular Pharmacology
The overarching goal of the Lassar lab is to understand how different cells types (i.e., articular or epiphyseal chondrocytes, ligaments and synoviocytes...
Our major goal is to understand how lncRNAs interact with chromatin complexes to achieve locus-specific and temporally specific gene expression patterns. We... Read more about Jeannie T. Lee
My research laboratory is a part of the Brigham Regenerative Medicine Center, a research program I direct. My laboratory's approach is to understand important... Read more about Richard Theodore Lee
Research in the Levy Lab focuses on endogenous mechanisms for resolution of lung inflammation and injury. The laboratory's overall mission is to identify...