The Mekalanos laboratory is engaged in the analysis of bacterial virulence and functional genomics. The goal of these studies is to understand how pathogenic... Read more about John Joseph Mekalanos
Xander University Professor of Stem Cell and Regenerative Biology
Research in our laboratory focuses on the developmental biology of the pancreas. We wish to understand how the pancreas normally develops and use that... Read more about Douglas A. Melton
My lab explores signal transduction pathways in the cells and tissues of the cardiovascular system. We have a particular focus on applying biochemical methods... Read more about Thomas M. Michel
Cancer represents one of the biggest problems for modern societies. In 2010, there were 1.53 million new cancer cases and 570,000 cancer-related deaths in...
My lab is interested in the structure, dynamics, and function of the cytoskeleton. We use imaging-based assays in living cells and in vitro extracts, in... Read more about Timothy J. Mitchison
We are interested in epigenetic mechanisms that control cellular memory and genome stability in eukaryotes and use yeast and mammalian cells as model...
in situ single-cell transcriptomic techniques offer the exciting ability to characterize gene expression within single cells in their native tissue context.... Read more about Jeffrey Moffitt
Mitochondria are tiny organelles found in nearly all cells, serving as the center stage for ATP production, ion homeostasis, and apoptosis. Their composition,... Read more about Vamsi K. Mootha
William Lambert Richardson Professor of Obstetrics, Gynecology and Reproductive Biology
Several long-term research projects in human genetics are ongoing in the Morton laboratory. An overall theme is to apply evolving techniques in molecular... Read more about Cynthia Casson Morton
Laurel Schwartz Professor of Medicine in the Field of Oncology
Cells need to accurately maintain their nuclear DNA in order to function properly. Indeed, defects in DNA integrity are associated with cancer, aging, and...
We are interested in the mechanisms by which cells regulate their gene expression patterns stably and heritably. Stable inheritance of distinct transcriptional... Read more about Mo R. Motamedi
The Mullally laboratory is a translational oncology lab focused on the study of myeloid blood cancers, primarily myeloproliferative neoplasms (MPN). We employ... Read more about Ann Mullally
The vast majority of RNAs encoded by the human genome are never translated into protein, and our laboratory focuses on understanding how these noncoding...
Our laboratory researches how cancer cells develop drug resistance, and more specifically, how the tumor microenvironment provides support and protection...
Though it has historically focused on fundamental biological questions, the Novina lab places a significant emphasis on identifying unmet medical needs...
The vertebrate immune system is capable of specifically recognizing and responding to an enormous number of antigens. The interaction with antigen is...
