Our laboratory studies molecular control of development and cell differentiation using self-renewing epithelia in the digestive tract as a model system...
Elliott T. and Onie H. Adams Professor of Biochemistry and Systems Biology
What can we build with biology? We use a synthetic biology approach to understanding biological systems through design, making new biological structures...
Why do we grow old? Why does aging cause disease? Can we slow aging or even reverse it? These are some of the greatest unsolved questions in biology....
Shields Warren-Mallinckrodt Professor of Medical Research
My lab has pioneered various aspects of the microRNA field and continues to make important contributions to this aspect of post-transcriptional control of gene... Read more about Frank John Slack
Using a combination of computational and experimental approaches we study the processes that determine whether mammalian cells live or die. Our lab is...
Diabetes and Obesity Genetics. The Soukas Laboratory in the Center for Human Genetic Research and the Diabetes Unit at the MGH seeks to understand the...
My research focuses on understanding the relationship between genotype and phenotype, with a special interest in how biochemistry, molecular design, and...
Latham Family Professor of Biological Chemistry and Molecular Pharmacology
We work on receptor-ligand interactions and signal transmission across membranes. We use a wide range of structural, cell biological, and single molecule...
David Wesley Gaiser Professor of Biological Chemistry and Molecular Pharmacology
Transcriptional regulation in response to environmental and developmental cues is mediated by the combinatorial and synergistic action of specific DNA-...
For a living cell to function properly, its cellular processes must be strictly controlled not only in time but also in space. We are interested in how...
Data generated by the rapidly advancing DNA sequencing technology provide the complete picture of population genetic variation and sequence divergence...
My laboratory is focused on the biology of brain tumors, in particular glioblastoma and oligodendroglioma. My group is dissecting how cellular heterogeneity... Read more about Mario L. Suvà
We study immune signaling pathways to understand the role of innate immune cells in liver diseases. Our studies focus on molecular mechanisms of inflammation... Read more about Gyongyi Szabo
The major focus of our laboratory is to investigate the cell and molecular biology of cancer, with a focus on the PI 3-Kinase and AKT signaling pathway in...
Obesity is an epidemic health problem worldwide and is a significant risk factor for many human diseases, including diabetes, dyslipidemias, non-alcoholic... Read more about Yu-Hua Tseng
Within cells macromolecules form complex intertwined networks of functionally interacting components. The molecular mechanisms underlying biological...
