#  3D Map of Cell Signaling Sites Could Help Improve Cancer Treatment 

 





Tool can identify kinase activity in cancer cells, inform use of kinase inhibitors



 

August 26, 2026

 

 

Cell-communication molecules called kinases play a key role in the growth and spread of many cancers. But exactly which kinases are active in a particular cancer is not always clear — there are 1.8 million sites on human proteins that kinases might act on, and researchers have fully characterized less than 1 percent of them.

A Harvard Medical School team has now built an AI-enabled tool called KinoPlex that maps the three-dimensional structures and biochemical environments of all of these sites and matches them with the specific kinases that can interact with them.

Read [full article](https://hms.harvard.edu/news/3d-map-cell-signaling-sites-could-help-improve-cancer-treatment?utm_source=OCERMarketingCloud&utm_medium=email&utm_campaign=08.25.2026-HMNews&utm_content=3D+Map+of+Cell+Signaling+Sites+Could+Help+Improve+Cancer+Treatment).



 

 

 



 

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