#  New Screening Approach Expands Search for Compounds That Destroy Disease-Causing Proteins 

 





Platform identifies molecular glue degraders, which harness cells’ waste disposal systems



 

August 26, 2026

 

 

Harvard Medical School investigators at Dana-Farber Cancer Institute have developed a new laboratory method for systematically discovering molecular glue degraders — compounds that harness cells’ own waste-disposal machinery to destroy disease-causing proteins, including proteins that have been difficult to target with traditional drugs.

The new platform, reported Aug. 5 in Nature, could dramatically expand the search for molecular glue-based drugs, including protein degraders. Already, it has revealed a new way that molecular glue degraders can work.

Read [full article](https://hms.harvard.edu/news/new-screening-approach-expands-search-compounds-destroy-disease-causing-proteins?utm_source=OCERMarketingCloud&utm_medium=email&utm_campaign=08.25.2026-HMNews&utm_content=New+Screening+Approach+Expands+Search+for+Compounds+That+Destroy+Disease-Causing+Proteins).



 

 

 



 

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