I am the director of urology research at Boston Children's Hospital and a cell biologist and biochemist by training. Research in my laboratory focuses on...
Certain genetic disorders cause widespread disease in the body, but the principle reason for illness and death in early childhood is failure of the blood...
Messenger RNA is in constant flux between different locations and states -- the nucleus and cytoplasm, activation and silencing, translation and decay.... Read more about Paul Joseph Anderson
There is now overwhelming evidence indicating that VEGF, TGFβ, PDGF, and Notch among others, the molecules that are essential for vascular formation, are...
Though much of what defines a human is encoded in the sequence of our DNA, many additional factors influence how this genetic information is manifest. For... Read more about Bradley E. Bernstein
My laboratory is focused on endothelial cells and how they become disrupted in disease. We also study a normal, yet highly proliferative endothelial cell...
Gustavus Adolphus Pfeiffer Professor of Biological Chemistry and Molecular Pharmacology
The long-term goal of our research program is to understand the molecular logic of signal transduction, focusing on proteins implicated in human disease. The... Read more about Stephen Charles Blacklow
Most of our genome is highly repetitive sequence derived from the activities of selfpropagating retrotransposons. Research in the Burns lab focuses on...
Hematopoiesis serves as a useful model system for studies of cell fate determination and lineage plasticity. Lineage-specific transcription factors play...
We seek to elucidate mechanisms of disease and develop novel therapeutics through understanding underlying processes of innate and adaptive immunity...
My laboratory is interested in mechanisms and therapy of cancers. In the past years, I have been working on different types of hematologic and solid...
Our research focuses on new technologies for genomic & proteomic measurement, synthesis and modeling of biomedical & ecological systems -- in... Read more about George Mcdonald Church
Professor of Biological Chemistry and Molecular Pharmacology
Our laboratory takes molecular approaches to herpesvirus replication and latency. These studies provide excellent models for biological processes in...
The D'Amore laboratory has a long-standing interest in the regulation of vascular development and pathology. One major area has involved investigating the role... Read more about Patricia Ann D'Amore
Alvan T. and Viola D. Fuller American Cancer Society Professor of Radiation Oncology
Our laboratory examines the molecular signaling pathways which regulate the DNA damage response in mammalian cells. Disruption of these pathways, by...