The Fontana lab has two main goals. First, understand the dynamical processes that constitute and maintain biological organization in terms of...

We work on positive strand RNA viruses, with a current focus on understanding how cells sense viral invaders to initiate an immune response. We also have...

Recent advances in genomics now make it possible to consider enumerating all of the genetic lesions in specific cancers. High throughput approaches are...

Bacterial pathogens that grow within human cells are responsible for multiple diseases and millions of deaths worldwide. The primary goal of our research...

The overall goal of our research is to understand the role of the tumor microenvironment, including the tumor vasculature and matrix, in tumor growth and...

The overarching goal of the Jost lab is to define the molecular mechanisms of host-microbiome communication using a combination of systematic CRISPR...