# Marissa Gredler Assistant Professor of Molecular and Cellular Biology ![Gredler](/sites/g/files/omnuum5321/files/styles/hwp_4_5__480x600/public/2025-06/Gredler%20Photo.jpg?itok=HSw9hZQQ) smartphone [617-495-2114](tel:617-495-2114) email laptop\_windows [Lab](https://gredlerlab.com/) laptop\_windows [Publications](https://www.ncbi.nlm.nih.gov/myncbi/marissa.gredler.2/bibliography/public/) Harvard University Northwest Building 355.40 52 Oxford Street Cambridge, MA 02138 The Gredler lab investigates how dynamic cellular behaviors generate complex tissue structures during vertebrate development. We focus on the developing mouse embryo as a model to understand how cells coordinate their behaviors in space and time to drive morphogenesis. We are particularly interested in how mechanical and molecular signals are integrated by cells in real-time to sculpt embryonic tissues. Our current projects explore: - The role of cell polarization in epithelial morphogenesis and tissue formation - The coordination of cell movements during axis elongation and body plan establishment - Mechanisms that confer robustness and plasticity to collective cell behaviors To address these questions, we combine high-resolution 4D imaging with targeted genetic and molecular perturbations. Our lab is equipped for advanced mouse embryo dissection and culture, time-lapse imaging, and custom image analysis workflows. Our long-term goal is to decode the principles by which coordinated cell behaviors drive robust developmental outcomes, with implications for regenerative medicine, congenital disease, and tissue engineering. - ## Program Affiliation [Developmental and Regenerative Biology](/bbs-faculty/developmental-and-regenerative-biology) - ## Discipline [Cell Biology](/discipline/cell-biology) [Developmental Biology](/discipline/developmental-biology) [Genetics](/discipline/genetics) [Imaging](/discipline/imaging) - ## Organism [Mouse](/organism/mouse) - ## People [Faculty](/people/faculty) - ## Location [Harvard University](/location/harvard-university)