# Michael Talkowski Professor of Neurology ![Mike](/sites/g/files/omnuum5321/files/styles/hwp_4_5__480x600/public/2024-10/Untitled%2010.jpg?itok=FQLlzwnm) smartphone [617-643-3097](tel:617-643-3097) email Massachusetts General Hospital Richard B. Simches Research-5.234 185 Cambridge St. Boston, MA 02114 Genomics of human disease. We are interested in the functional consequences of the complete spectrum of genomic variation on human disease, with a particular focus on congenital birth defects, autism, neurodevelopmental disorders, and diverse neuropsychiatric disorders. The lab has a structural variation group, a functional genomics group, and a team dedicated to translating genomics technologies for genetic diagnostic, primarily prenatal and neonatal diagnostic sequencing. - ## Program Affiliation [Genetics](/bbs-faculty/genetics) - ## Discipline [Genetics](/discipline/genetics) [Genomics](/discipline/genomics) - ## Organism [Human](/organism/human) [Mouse](/organism/mouse) - ## People [Faculty](/people/faculty) - ## Location [Massachusetts General Hospital](/location/massachusetts-general-hospital)