Bacterial pathogens that grow within human cells are responsible for multiple diseases and millions of deaths worldwide. The primary goal of our research...
Immune cell modulation is an attractive strategy for the treatment of inflammatory conditions. Inflammation is critical to protecting us from dangers...
The increasing emergence of bacterial strains resistant to antibiotics is far outpacing our ability to develop novel therapies to treat these infections....
Director, Wyss Institute for Biologically Inspired Engineering
My laboratory is interested in how microenvironmental cues, particularly mechanical forces and extracellular matrix, regulate tissue development, physiology... Read more about Donald Elliot Ingber
The overarching goal of the Jost lab is to define the molecular mechanisms of host-microbiome communication using a combination of systematic CRISPR...
Ancient signaling pathways lie at the base of the initiation of immunity, serving to transmit signals from Pattern Recognition Receptors (PRRs) to trigger the... Read more about Jonathan C. Kagan
Professor of Biological Chemistry and Molecular Pharmacology
For many years our research group has been interested in the molecular mechanisms of various antibiotics and the fundamental cellular processes they inhibit.... Read more about Daniel Kahne
William Ellery Channing Professor of Medicine and Professor of Immunology
My laboratory has long been interested in the interactions of microbes, both commensals and pathogens, with the immune system. Our overall major research...
Our studies have spanned evolutionarily conserved pathways of innate immunity, the integrative physiology that connects infection and immunity with cellular... Read more about Dennis Kim
Assistant Professor of Biological Chemistry and Molecular Pharmacology
Research in our lab takes a bottom-up approach to tackling molecular challenges in cancer biology. Basic chemical research – development of new reactions,... Read more about Justin Kim
Our research focuses on the processes that mediate and regulate the movement of membrane proteins throughout cells. In particular our studies have help...