My lab studies how organisms defend against environmental and metabolic stresses, and how these stress defenses influence aging. Most of our work involves...
Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology
The laboratory focuses on understanding how small molecules, particularly those from bacteria and fungi, control biological processes. Organizing themes...
Bert and Natalie Vallee Professor of Molecular Pathology
Ubiquitin and ubiquitin-like (UBL) protein conjugation systems control a vast array of cellular processes, and impact virtually every biological system....
Work in my lab is focused on understanding how signals in the brain lead to particular patterns of behavior. We utilize a combination of behavioral,...
Organisms possess a blueprint for life, which they transmit to their progeny. DNA (genetic information) is a major constituent of life's blueprint. It is...
Our studies have spanned evolutionarily conserved pathways of innate immunity, the integrative physiology that connects infection and immunity with cellular... Read more about Dennis Kim
Shields Warren-Mallinckrodt Professor of Medical Research
My lab has pioneered various aspects of the microRNA field and continues to make important contributions to this aspect of post-transcriptional control of gene... Read more about Frank John Slack
Diabetes and Obesity Genetics. The Soukas Laboratory in the Center for Human Genetic Research and the Diabetes Unit at the MGH seeks to understand the...
Within cells macromolecules form complex intertwined networks of functionally interacting components. The molecular mechanisms underlying biological...
Our laboratory studies how chromosome behavior and positioning influence genome function and evolution, with implications for gene regulation, genome...