Brain tumors are the leading cause of cancer related death in childhood. Children that do survive are frequently left with life-long and devastating... Read more about Pratiti Bandopadhayay
Cancer cells display remarkable plasticity allowing them to adapt to ever changing environments. A key feature of this plasticity is their ability to...
Work in the Barczak lab focuses on the molecular pathogenesis of Mycobacterium tuberculosis. After COVID-19, tuberculosis is the leading cause of death...
Harold T. White Professor of Biological Chemistry and Molecular Pharmacology
The bithorax complex in the fruit fly is a cluster of “homeotic” genes which confer distinct identities on the different segments of the fly. The genes...
Richard and Susan Smith Distinguished Professor of Medicine
In erythrocytes, Protein 4.1R is essential for membrane integrity. Deficiencies cause congenital hemolytic anemia. We have shown that there are many isoforms... Read more about Edward Benz
Bacterial cells come in a wide variety of shapes and sizes. Within a given class, however, cells typically grow and divide in such a way as to maintain...
Though much of what defines a human is encoded in the sequence of our DNA, many additional factors influence how this genetic information is manifest. For... Read more about Bradley E. Bernstein
The Bhattacharyya lab focuses on characterizing the response of pathogens (bacteria and fungi) to antimicrobials, and of patients to systemic infections,...
My laboratory is focused on endothelial cells and how they become disrupted in disease. We also study a normal, yet highly proliferative endothelial cell...
Gustavus Adolphus Pfeiffer Professor of Biological Chemistry and Molecular Pharmacology
The long-term goal of our research program is to understand the molecular logic of signal transduction, focusing on proteins implicated in human disease. The... Read more about Stephen Charles Blacklow
My lab studies how organisms defend against environmental and metabolic stresses, and how these stress defenses influence aging. Most of our work involves...
As a physician-scientist caring for children with chronic disease I am acutely aware of the burden caused by these conditions and the need for improved... Read more about David T. Breault