Harold T. White Professor of Biological Chemistry and Molecular Pharmacology
The bithorax complex in the fruit fly is a cluster of “homeotic” genes which confer distinct identities on the different segments of the fly. The genes...
Richard and Susan Smith Distinguished Professor of Medicine
In erythrocytes, Protein 4.1R is essential for membrane integrity. Deficiencies cause congenital hemolytic anemia. We have shown that there are many isoforms... Read more about Edward Benz
Bacterial cells come in a wide variety of shapes and sizes. Within a given class, however, cells typically grow and divide in such a way as to maintain...
Though much of what defines a human is encoded in the sequence of our DNA, many additional factors influence how this genetic information is manifest. For... Read more about Bradley E. Bernstein
My laboratory is focused on endothelial cells and how they become disrupted in disease. We also study a normal, yet highly proliferative endothelial cell...
Gustavus Adolphus Pfeiffer Professor of Biological Chemistry and Molecular Pharmacology
The long-term goal of our research program is to understand the molecular logic of signal transduction, focusing on proteins implicated in human disease. The... Read more about Stephen Charles Blacklow
My lab studies how organisms defend against environmental and metabolic stresses, and how these stress defenses influence aging. Most of our work involves...
As a physician-scientist caring for children with chronic disease I am acutely aware of the burden caused by these conditions and the need for improved... Read more about David T. Breault
General anesthesia is a neurophysiological state in which a patient is rendered unconscious, insensitive to pain, amnestic, and immobile, while being... Read more about Emery Neal Brown
Associate Professor of Biological Chemistry and Molecular Pharmacology
We are interested in understanding transport mechanisms in the cell. In particular, we are interested in how molecules are transported into, out of, and...
The primarily focus of the work in my laboratory is the molecular understanding of the action of steroid hormone receptors and their role in human cancer. We... Read more about Myles Brown
Assistant Professor of Stem Cell and Regenerative Biology
Our laboratory seeks to advance our understanding of gene regulation biology using single-cell methods. To do this, we develop new technologies that integrate... Read more about Jason Daniel Buenrostro
Associate Professor of Biological Chemistry and Molecular Pharmacology
Dysregulation of protein homeostasis drives many types of cancer, infection and neurodegeneration. The ubiquitin system performs a central role in maintenance... Read more about Sara Buhrlage
Although numerous eukaryotic genomes have been sequenced, much still remains to be understood about how the genes in those genomes are regulated. The...
Professor of Biological Chemistry and Molecular Pharmacology
Our lab studies eukaryotic gene expression. We are concentrating on three areas: (A) the functions and interactions of the RNA polymerase II (RNApII)...
Research in the Burns Laboratory is devoted to understanding how cardiovascular progenitor cells build the vertebrate heart during embryonic development...