Dorothy and Milton Flier Professor of Biomedical Science and Genetics
We are working to understand (i) how the human genome varies from person to person, and (ii) how inherited genome variation affects the biology of neurons...
The Megason Lab uses imaging-based systems biology to elucidate the systems level principles of animal development. We are particularly interested in long...
Mitochondria are tiny organelles found in nearly all cells, serving as the center stage for ATP production, ion homeostasis, and apoptosis. Their composition,... Read more about Vamsi K. Mootha
Though it has historically focused on fundamental biological questions, the Novina lab places a significant emphasis on identifying unmet medical needs...
The O’Donnell-Luria laboratory studies how genetic variation contributes to the development of rare disease in humans. While individually rare, these...
The vertebrate immune system is capable of specifically recognizing and responding to an enormous number of antigens. The interaction with antigen is...
I am a computational biologist studying the role of chromatin structure/dynamics and non-coding regions including enhancers, promoters, insulators and...
Despite the growing recognition of the importance of the microbiota to humans, there are fundamental aspects of the microbiota and its relation to the...
Immune-mediated diseases such as lupus or rheumatoid arthritis are not caused by an isolated insult resulting in a single dysfunctional gene or pathway,...