Professor of Biological Chemistry and Molecular Pharmacology
The Adelman lab aims to elucidate how cells react in a rapid yet balanced manner to external signals, at the transcriptional and epigenetic level. We use...
We are a collaborative group of genome editing scientists at the Translational Neuroscience Center of Boston Children’s Hospital and Harvard Medical...
Associate Professor of Biological Chemistry and Molecular Pharmacology
Protein-Protein Interactions (PPIs) is the Holy Grail of therapeutic intervention, offering a plethora of distinct structural landscapes that can be targeted... Read more about Haribabu Arthanari
Harold T. White Professor of Biological Chemistry and Molecular Pharmacology
The bithorax complex in the fruit fly is a cluster of “homeotic” genes which confer distinct identities on the different segments of the fly. The genes...
Gustavus Adolphus Pfeiffer Professor of Biological Chemistry and Molecular Pharmacology
The long-term goal of our research program is to understand the molecular logic of signal transduction, focusing on proteins implicated in human disease. The... Read more about Stephen Charles Blacklow
Associate Professor of Biological Chemistry and Molecular Pharmacology
We are interested in understanding transport mechanisms in the cell. In particular, we are interested in how molecules are transported into, out of, and...
Associate Professor of Biological Chemistry and Molecular Pharmacology
Dysregulation of protein homeostasis drives many types of cancer, infection and neurodegeneration. The ubiquitin system performs a central role in maintenance... Read more about Sara Buhrlage
Professor of Biological Chemistry and Molecular Pharmacology
Our lab studies eukaryotic gene expression. We are concentrating on three areas: (A) the functions and interactions of the RNA polymerase II (RNApII)...
Hematopoiesis serves as a useful model system for studies of cell fate determination and lineage plasticity. Lineage-specific transcription factors play...
Professor of Biological Chemistry and Molecular Pharmacology
Our research focuses on the molecular mechanism of membrane channels, receptors, and transporters. We have been using solution NMR spectroscopy to study...
Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology
The laboratory focuses on understanding how small molecules, particularly those from bacteria and fungi, control biological processes. Organizing themes...
Professor of Biological Chemistry and Molecular Pharmacology
Our laboratory takes molecular approaches to herpesvirus replication and latency. These studies provide excellent models for biological processes in...
Professor of Medicine Chief, Division of Gastroenterology, Hepatology and Endoscopy
The objective of our research is to understand the molecular and cellular mechanisms whereby intracellular membrane lipid composition regulates lipid and...
Our research involves the chemical biology of protein post-translational modifications (PTMs) in the context of signaling, epigenetics, and cancer. We develop... Read more about Philip Cole